TABLE 1.
Baseline characteristics of the sample population
| Period A | Period B | Period C | P‐value | |
|---|---|---|---|---|
| All patients | n = 725 | n = 469 | n = 522 | |
| Age, y, mean ± SD | 71.4 ± 13.4 | 70.7 ± 13.6 | 71.7 ± 13.8 | .48 |
| Men, n (%) | 389 (53.7) | 250 (53.3) | 264 (50.6) | .53 |
| Preadmission mRS score, median (IQR) | 0 (0‐2) | 0 (1‐3) | 0 (0‐1) | .30 |
| Body mass index, kg/m2, mean ± SD | 22.4 ± 3.8 | 22.7 ± 4.5 | 22.7 ± 4.1 | .46 |
| Current smoker, n (%) | 202 (27.9) | 153 (32.6) | 168 (32.2) | .14 |
| Glasgow Coma Scale score, n (%) | ||||
| E 4 | 483 (66.6) | 291 (62.1) | 298 (57.1) | .007 |
| E 2–3 | 134 (18.5) | 107 (22.8) | 118 (22.6) | |
| E 1 | 108 (14.9) | 71 (15.1) | 106 (20.3) | |
| Patients without neurosurgical treatment | n = 676 | n = 424 | n = 442 | |
| Age, y, mean ± SD | 72.0 ± 13.1 | 71.3 ± 13.4 | 72.5 ± 13.7 | .45 |
| Men, n (%) | 369 (53.1) | 223 (52.6) | 221 (50.0) | .58 |
| Preadmission mRS score, median (IQR) | 0 (0–2) | 0 (1–3) | 0 (0–1) | .71 |
| Body mass index, kg/m2, mean ± SD | 22.4 ± 3.8 | 22.8 ± 4.6 | 22.5 ± 4.1 | .34 |
| Current smoker, n (%) | 184 (28.8) | 136 (33.9) | 131 (31.5) | .14 |
| Glasgow Coma Scale score, n (%) | ||||
| E 4 | 469 (69.4) | 279 (65.8) | 278 (62.9) | .22 |
| E 2–3 | 115 (17.0) | 86 (20.3) | 92 (20.8) | |
| E 1 | 92 (13.6) | 59 (13.9) | 72 (16.3) |
Abbreviations: E, eye response component; IQR, interquartile range; mRS, modified Rankin scale.