Table 1. The baseline characteristics of lung adenocarcinoma patients in this study.
Parameter | TCGA cohort | GEO cohort 1 | GEO cohort 2 |
---|---|---|---|
Database | TCGA | GSE68465 | GSE41271 |
Gender | |||
Female | 251 (54.92%) | 211 (50.00%) | 90 (49.72%) |
Male | 206 (45.08%) | 211 (50.00%) | 91 (50.28%%) |
Age | |||
≤65 | 233 (50.98%) | 219 (51.90%) | 102 (56.35%) |
>65 | 224 (49.02%) | 203 (48.10%) | 79 (43.65%%) |
Smoking | |||
Never | 61 (13.35%) | 48 (11.37%) | 26 (14.36%) |
Ever | 379 (82.93%) | 288 (68.25%) | 155 (85.64%%) |
NA | 12 (2.62%) | 86 (20.38%) | 0 |
TNM stage | |||
I | 262 (57.33%) | 267 (63.27%) | 100 (55.25%) |
II | 102 (22.32%) | 95 (22.51%) | 28 (15.47%) |
III | 70 (15.32%) | 60 (14.22%) | 49 (27.07%) |
IV | 23 (5.03%) | 0 | 4 (2.21%) |
Tumor size | |||
T1 | 149 (32.60%) | 146 (34.60%) | NA |
T2 | 241 (52.74%) | 238 (56.40%) | NA |
T3 | 49 (10.72%) | 27 (6.40%) | NA |
T4 | 18 (3.93%) | 11 (2.60%) | NA |
NA | 0 | 0 | 181 (100%) |
Lymph node | |||
N0 | 311 (68.05%) | 289 (68.48%) | NA |
N1-3 | 146 (31.95%) | 133 (31.52%) | NA |
NA | 0 | 0 | 181 (100%) |
Metastasis | |||
M0 | 434 (94.97%) | 422 (100%) | NA |
M1 | 23 (5.03%) | 0 | NA |
NA | 0 | 0 | 181 (100%) |
Survival status | |||
Alive | 306 (66.96%) | 193 (45.73%) | 112 (61.88%%) |
Dead | 151 (33.04%) | 229 (54.27%%) | 69 (38.12%) |
Risk score | |||
Low | 272 (59.52%) | 89 (21.09%) | 122 (67.40%) |
High | 185 (40.48%) | 333 (78.91%) | 59 (32.60%) |
Total | 457 (100%) | 422 (100%) | 181 (100%) |
Note:
TCGA, The Cancer Genome Altas; GEO, Gene Expression Omnibus; NA, represents information not available.