Table 2.
Patients with hepatitis B-related cirrhosis (n = 160) | ||
---|---|---|
Diagnostic indexes | All size varices | High-risk varices |
AUC (95% CI) | 0.834 (0.767-0.888) | 0.881 (0.820-0.927) |
‡Cut-off values | 11.4 kPa | 14.50 kPa |
Sensitivity | 0.77 (0.61-0.88) | 0.77 (0.56-0.91) |
Specificity | 0.80 (0.72-0.87) | 0.91 (0.85-0.95) |
PPV | 0.59 (0.45-0.72) | 0.63 (0.44-0.79) |
NPV | 0.90 (0.83-0.95) | 0.95 (0.90-0.98) |
Positive LR | 3.9 (2.6-5.8) | 8.6 (4.8-15.3) |
Negative LR | 0.3 (0.2-0.5) | 0.3 (0.1-0.5) |
Note: data in parentheses are 95% confidence intervals. ‡A cut-off was set to maximize the sum of sensitivity and specificity. Abbreviations: PPV: positive predictive value; NPV: negative predictive value; LR: likelihood ratio; CI: confidence interval.