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. Author manuscript; available in PMC: 2021 Jul 1.
Published in final edited form as: Clin Cancer Res. 2020 Oct 12;27(1):213–225. doi: 10.1158/1078-0432.CCR-20-2868

Figure 4: Expression levels of cyclin D1-dependent program correlate with survival in MCL patients.

Figure 4:

(A) Association between the 295-gene cyclin D1 signature score and the death risk in MCL primary cases, from both peripheral blood and lymphoid tissue samples. The death risk (y-axis) corresponds to the sum of the martingale residuals and the linear predictors of the fitted OS Cox model; hazard ratios (HR) with 95% confidence interval and p-values are shown. (B) Kaplan-Meier curves of OS from diagnosis date corresponding to 295-gene cyclin D1 signature high and low MCL groups, in peripheral blood (high n = 16; low n = 30) and lymphoid tissue (high n = 40; low n = 52) samples.