Kaplan-Meier estimates of cumulative probabilities of return to ovulation, with 95% confidence intervals and numbers at risk below the x-axis. The estimated probabilities at month 12 were 65%, 25%, and 11% in the 150 mg, 300 mg, and Depo-SubQ 104 groups, respectively (P = .009 for test of difference in distributions across groups). The earliest ovulation occurred on day 226 in the 150 mg group (median = 320 days). All doses were administered subcutaneously. The Depo-SubQ 104 group received a second injection on day 91.