Table 2.
The survival analysis of CRC patients.
| Univariate | Multivariate | |||||
| n | 5-yr OS rate | P | HR | 95%CI | P | |
| Age (yr) | .88 | |||||
| ≥60 | 153 | 66.8% | ||||
| <60 | 190 | 72.3% | ||||
| Gender | . 24 | |||||
| Male | 211 | 72.5% | ||||
| Female | 132 | 71.8% | ||||
| Tumor site | .41 | |||||
| Colon | 127 | 70.6% | ||||
| Rectum | 216 | 69.5% | ||||
| Tumor size (cm) | .16 | |||||
| ≥5 | 126 | 69.3% | ||||
| <5 | 217 | 72.8% | ||||
| Tumor invasion depth | .56 | |||||
| T1+T2 | 181 | 75.7% | ||||
| T3+T4 | 162 | 69.6% | ||||
| Lymph node involvement | .01 | |||||
| N0 | 139 | 74.8% | ||||
| N1 | 204 | 67.3% | ||||
| Clinical Stage | .03 | 4.37 | 3.98–12.33 | <.01 | ||
| I+II | 150 | 75.3% | ||||
| III | 203 | 64.2% | ||||
| Pathological differentiation | .03 | 1.28 | 1.01–6.63 | .01 | ||
| Well/Moderate | 208 | 76.2% | ||||
| Poor | 135 | 65.1% | ||||
| MiR-449a | .03 | 2.56 | 1.15–8.63 | <.01 | ||
| low | 226 | 67.4% | ||||
| high | 117 | 76.9% | ||||
| CEA (ng/ml) | <.01 | |||||
| ≥5 | 90 | 65.4% | ||||
| <5 | 253 | 75.8% | ||||
| CA19–9 (ng/ml) | <.01 | 2.15 | 1.02–8.88 | .02 | ||
| ≥38 | 94 | 64.3% | ||||
| <38 | 249 | 76.1% | ||||