Table 1.
Clinical data of 561 patients with sICH.
| Total | Male | Female | χ2/F/z/t | P | ||
| Total | n (%) | 561 | 360 (64.17) | 201 (35.83) | ||
| Age (yr) | 63.2 ± 12.4 | 62.3 ± 12.5 | 64.9 ± 12.1 | 2.439∗ | .015 | |
| Age group (yr) | 5.655† | .130 | ||||
24–39 
|
12 (2.14) | 8 (2.22) | 4 (1.99) | |||
40–59 
|
214 (38.15) | 150 (41.67) | 64 (31.84) | |||
60–79 
|
278 (49.55) | 169 (46.94) | 109 (54.23) | |||
80–96 
|
57 (10.16) | 33 (9.16) | 24 (11.94) | |||
| Onset season | 2.481† | .479 | ||||
| Spring | 154 (27.45) | 99 (27.50) | 55 (27.36) | |||
| Summer | 111 (19.79) | 77 (21.39) | 34 (16.92) | |||
| Autumn | 133 (23.71) | 86 (23.89) | 47 (23.38) | |||
| Winter | 163 (29.06) | 98 (27.22) | 65 (32.34) | |||
| Time to hospital encounter (h) | Median (P25, P75 ) | 3.00 (2.00, 5.00) | 3.00 (2.00, 5.00) | 3.00 (2.00, 4.00) | 0.527‡ | .598 |
| Hypertension | ||||||
| No | 297 (52.94) | 200 (55.56) | 97 (48.26) | 2.757† | .097 | |
| Yes | 264 (47.06) | 160 (44.44) | 104 (51.74) | |||
| Duration (yr) | Median (P25, P75 ) | 5.0 (3.0, 10.0) | 5.0 (3.0, 10.0) | 5.0 (3.0, 10.0) | 0.639‡ | .523 |
| Treatment | ||||||
| Regularly | 46 (17.42) | 26 (16.25) | 20 (19.23) | 0.496† | .780 | |
| Unregularly | 161 (60.98) | 100 (62.50) | 61 (58.65) | |||
| No | 57 (21.59) | 34 (21.25) | 23 (22.12) | |||
| Result | ||||||
| Reached | 10 (4.83) | 8 (6.35) | 2 (2.47) | 1.623† | .444 | |
| Unreached | 33 (15.94) | 20 (15.87) | 13 (16.05) | |||
| Unknown | 164 (79.23) | 98 (77.78) | 66 (81.48) | |||
| Admission systolic pressure (mm Hg) | Median (P25, P75 ) | 178.0 (155.0,198.0) | 177.0 (153.0,199.8) | 178.0 (157.5,197.0) | 0.438‡ | .661 |
| Admission diastolic pressure (mm Hg) | Median (P25, P75 ) | 98.0 (85.5,109.0) | 99.0 (85.3,110.0) | 96.0 (85.5,106.0) | 1.731‡ | .087 |
| Diabetes | ||||||
| No | 534 (95.19) | 343 (95.28) | 191 (95.02) | 0.018† | .893 | |
| Yes | 27 (4.81) | 17 (4.72) | 10 (4.98) | |||
| Duration (yr) | 7.7 ± 5.8 | 5.9 ± 3.9 | 10.8 ± 7.4 | 10.663∗ | .003 | |
| Treatment | ||||||
| Regularly | 8 (29.63) | 5 (29.41) | 3 (30.00) | 0.173† | .917 | |
| Unregularly | 7 (25.93) | 4 (23.53) | 3 (30.00) | |||
| No | 12 (44.44) | 8 (47.06) | 4 (40.00) | |||
| Result | ||||||
| Reached | 6 (40.00) | 3 (33.33) | 3 (50.00) | 0.417† | .519 | |
| Unreached | 9 (60.00) | 6 (66.67) | 3 (50.00) | |||
| Admission blood glucose (mmol/L) | Median (P25, P75 ) | 7.31 (6.14, 8.94) | 7.02 (6.09 8.62) | 7.54 (6.19, 9.26) | 1.555‡ | .120 |
| Smoking | ||||||
| No | 353 (62.92) | 162 (45.00) | 191 (95.02) | 138.355† | <.001 | |
| Yes | 208 (37.08) | 198 (55.00) | 10 (4.98) | |||
| Duration (yr) | Median (P25, P75 ) | 30.0 (20.0, 40.0) | 30.0 (20.0, 40.0) | 30.0 (20.0, 35.0) | 0.711‡ | .477 |
| Daily smoking volume (cigarettes / day) | Median (P25,P75) | 20.0 (10.0, 20.0) | 20.0 (10.0, 20.0) | 9.0 (5.0, 16.3) | 2.444‡ | .015 |
| Drinking | ||||||
| No | 359 (63.99) | 172 (47.78) | 187 (93.03) | 114.654† | <.001 | |
| Yes | 202 (36.01) | 188 (52.22) | 14 (6.97) | |||
| Duration (yr) | Median (P25, P75 ) | 30.0 (20.0, 40.0) | 30.0 (20.0, 40.0) | 20.0 (5.0, 30.0) | 2.802‡ | .005 |
| Daily drinking volume (g/d) | Median (P25, P75 ) | 100.0 (93.8, 200.0) | 100.0 (81.3, 200.0) | 100.0 (87.5, 100.0) | 1.330‡ | .183 |
| Stroke | ||||||
| No | 500 (89.13) | 327 (90.83) | 173 (86.07) | 3.020† | .082 | |
| Yes | 61 (10.87) | 33 (9.17) | 28 (13.93) | |||
| Cerebral hemorrhage | 41 (67.21) | 21 (63.64) | 20 (71.43) | 0.481† | .786 | |
| Cerebral infarction | 17 (27.87) | 10 (30.30) | 7 (25.00) | |||
| Both | 3 (4.92) | 2 (6.06) | 1 (3.57) | |||
| Oral anticoagulant and/or antiplatelet drugs | ||||||
| No | 552 (98.40) | 355 (98.61) | 197 (98.01) | 0.295† | .587 | |
| Yes | 9 (1.60) | 5 (1.39) | 4 (1.99) | |||
| Aspirin | 6 (66.67) | 4 (80.00) | 2 (50.00) | 1.575† | .455 | |
| Clopidogrel | 2 (22.22) | 1 (20.00) | 1 (25.00) | |||
| Warfarin | 1 (11.11) | 1 (25.00) | ||||
| BMI | Median (P25, P75 ) | 22.86 (20.81,24.66) | 23.03 (21.26,24.80) | 22.21 (20.03,24.03) | 2.912‡ | .004 |
| BMI group | 10.493† | .001 | ||||
| Normal | 370 (65.95) | 220 (61.11) | 150 (74.63) | |||
| Obese | 191 (34.05) | 140 (38.89) | 51 (25.37) | |||
| Liver function (ALT/AST) | ||||||
| Normal | 547 (97.50) | 352 (97.78) | 195 (97.01) | 0.308† | .579 | |
| Abnormal | 14 (2.50) | 8 (2.22) | 6 (2.99) | |||
| Renal function (CREA) | ||||||
| Normal | 538 (95.90) | 343 (95.28) | 195 (97.01) | 0.990† | .320 | |
| Abnormal | 23 (4.10) | 17 (4.72) | 6 (2.99) | |||
| Platelet (PLT) | ||||||
| Normal | 479 (85.38) | 308 (85.56) | 171 (85.07) | 0.024† | .877 | |
| Abnormal | 82 (14.62) | 52 (14.44) | 30 (14.93) | |||
| Blood coagulation function (PT/APTT/TT/FIB) | ||||||
| Normal | 556 (99.11) | 356 (98.89) | 200 (99.50) | 0.550† | .458 | |
| Abnormal | 5 (0.89) | 4 (1.11) | 1 (0.50) | |||
| Side of bleeding | ||||||
| Left | 295 (52.58) | 194 (53.89) | 101 (50.25) | 1.993† | 0.369 | |
| Right | 257 (45.81) | 162 (45.00) | 95 (47.26) | |||
| Bilateral | 9 (1.60) | 4 (1.11) | 5 (2.49) | |||
| Location of bleeding | ||||||
| Basal nucleus | 277 (49.38) | 186 (51.67) | 91 (45.27) | 21.171† | .048 | |
| Thalamus | 86 (15.33) | 50 (13.89) | 36 (17.91) | |||
| Brain stem | 47 (8.38) | 33 (9.17) | 14 (6.97) | |||
| Others | 151 (26.92) | 91 (25.28) | 60 (29.85) | |||
| Admission GCS (score) | Median (P25, P75 ) | 9.0 (7.0, 11.0) | 9.0 (7.0, 11.0) | 10.0 (7.0, 11.0) | 2.088‡ | .037 |
| Degree of disturbance of consciousness on admission | ||||||
| Mild | 115 (20.50) | 75 (20.83) | 40 (19.90) | 3.327† | .189 | |
| Moderate | 224 (39.93) | 134 (37.22) | 90 (44.78) | |||
| Severe | 222 (39.57) | 151 (41.94) | 71 (35.32) | |||
| Surgical treatment | ||||||
| Yes | 173 (30.84) | 114 (31.67) | 59 (29.35) | 0.324† | .569 | |
| No | 388 (69.16) | 246 (68.33) | 142 (70.65) | |||
| Length of stay (days) | Median (P25, P75 ) | 13.0 (4.0, 22.0) | 12.0 (4.0, 23.0) | 14.0 (5.0, 20.0) | 0.730‡ | .466 |
| Inpatient costs (USD) | Median (P25, P75 ) | 3608 (1760, 8541) | 3500 (1742, 8774) | 3912 (1870, 8359) | 0.450‡ | .652 |
| Prognosis after 30 d of onset (mRS) | ||||||
| Slight disability | 22 (3.92) | 19 (5.28) | 3 (1.49) | 11.558† | .021 | |
| Moderate disability | 97 (17.29) | 58 (16.11) | 39 (19.40) | |||
| Moderately severe disability | 219 (39.04) | 128 (35.56) | 91 (45.27) | |||
| Severe disability | 120 (21.39) | 82 (22.78) | 38 (18.91) | |||
| Dead | 103 (18.36) | 73 (20.28) | 30 (14.93) | |||