Table 5.
Results from Sensitivity Analysis: Mean Expected Additional Cost of Each Complication per Cataract Surgery per Patient Under a Single-Use Policy, a Reuse Policy and Its Difference Expressed in Euros
| Costs | Reuse of SUDs | Single Use of SUDs | Difference (Reuse-Single Use) |
|---|---|---|---|
| Monetary cost of cataract surgerya | 1,146.86 | 1,244.20 | −97.34 |
| Procedure/hospitalization | 973.94 | 973.94 | 0 |
| Medications | 13.86 | 13.86 | 0 |
| Postoperative visits | 156 | 156 | 0 |
| SUDs | - | 100.4 | −100.4 |
| Sterilization of SUDs per procedure | 3.06 | - | 3.06 |
| Adverse Events Costsb | 339.60 | 160.02 | 179.58 |
| Posterior Capsule Rent | 17.36 | 16.27 | 1.09 |
| Acute endophthalmitis | 11.42 | 1.53 | 9.89 |
| Chronic endophthalmitis | 28.27 | 4.97 | 23.31 |
| Cornea tunnel infection | 7.63 | 0.78 | 6.85 |
| Toxic anterior segment syndrome (TASS) | 37.42 | 1.58 | 35.84 |
| Prolonged postoperative inflammation | 2.44 | 1.12 | 1.32 |
| Cystoid macular edema | 52.46 | 36.72 | 15.74 |
| Elevated intraocular pressure on the first postoperative day | 2.65 | 2.24 | 0.41 |
| Postoperative hypotony due to a Seidel-positive corneal wound | 3.02 | 1.09 | 1.94 |
| Corneal edema due to endothelial cell loss in the immediate postoperative period | 93.44 | 62.74 | 30.69 |
| Corneal edema months to up to 1 year after the procedure due to endothelial cell loss | 34.06 | 7.45 | 26.60 |
| Phaco wound burn | 11.37 | 3.24 | 8.13 |
| Retinal detachment | 5.96 | 5.34 | 0.62 |
| Postoperative astigmatism | 32.10 | 14.95 | 17.15 |
| Total cost of cataract surgery (95% CI)c | * 1,486.47 (1,485.65 to 1,487.29) | ** 1,404.21 (1,403.70 to 1,404.72) | *** 82.26 (81.29 to 83.22) |
| Range | 1,349.58 to 1,669.28 | 1,319.71 to 1,512.17 | −100.53 to 280.02 |
Notes: aThis is the sum of the following subcosts: procedure/hospitalization, medications, postoperative visits, SUDs and their sterilization” bThis is the sum of the following adverse events’ subcosts: posterior capsule rent, acute endophthalmitis, chronic endophthalmitis, cornea tunnel infection, toxic anterior segment syndrome, prolonged postoperative inflammation, cystoid macular edema, elevated intraocular pressure on the first postoperative day, postoperative hypotony due to a Seidel-positive corneal wound, corneal edema due to endothelial cell loss in the immediate postoperative period, corneal edema months to up to 1 year after the procedure due to endothelial cell loss, phaco wound burn, retinal detachment and postoperative astigmatism. cThis is defined as the monetary cost of cataract surgery in each case plus the cost of adverse events, as listed above. It is displayed as the mean values and its 95% confidence interval based on the results from the sensitivity analysis. * Total cost of cataract surgery with SUD reuse = monetary cost of cataract surgery with SUD reuse + adverse events costs with SUDs reuse. ** Total cost of cataract surgery with SUD single use = monetary cost of cataract surgery with SUD single use + adverse events costs with SUD single use. *** Difference of total cost of cataract surgery between SUD reuse and single use = Total cost of cataract surgery with SUD reuse - Total cost of cataract surgery with SUD single use. The final results of the analysis are highlighted in bold.
Abbreviations: SUD, single use device; CI, confidence interval.