Table 2.

Parameter	Mean	RSE (%)	Description
Tlag (h)	0.512	8.48	Latency time
Ka (h−1)	0.523	8.54	Absorption constant
Cl/F (L/h)	30.3	8.25	Apparent clearance
β CL-CLCr	-0.204	43.7	$\text{loglog\hspace{0.17em}}\left(\text{CLi}\right)=\text{loglog\hspace{0.17em}}\left(\text{CLpop}\right)+{\beta }_{\text{CL}-\text{CLCr}}\ast \log \left(\frac{\text{CLCri}}{\text{CLCr}}\right)+{\eta }_{\text{CL}}$
Q/F (L/h)	17.0	12.1	Apparent clearance of distribution
V1 (L)	17.9	17.6	Apparent volume of central compartment
V2 (L)	400	45.6	Apparent volume of peripheral compartment
IIV Cl (%)	39.8	16.6	Interindividual variability of Cl
IIV Q (%)	53.2	18.7	Interindividual variability of Q
IOV Cl (%)	38.0	8.53	Interoccasion variability of Cl
IOV tlag (%)	54.1	12.4	Interoccasion variability of tlag
IOV ka (%)	52.6	9.85	Interoccasion variability of ka
Ka-Cl	-0.551	20.2	Correlation between Ka-Cl
Prop (%)	0.228	8.86	Proportional error
Add (ng/mL)	7.52	45.0	Additive error
AIC	6204		Akaike information criterion