Table 2.
Univariate analysis of factors associated with oral anticoagulant agent use among patients with nonvalvular atrial fibrillation.
| OACs not used | OACs used | p | |||
|---|---|---|---|---|---|
| N | % | N | % | ||
| Sex | 0.002 | ||||
| Male | 202 | 23.8% | 646 | 76.2% | |
| Female | 166 | 17.9% | 763 | 82.1% | |
| Age | <0.001 | ||||
| <50 years | 83 | 50.9% | 80 | 49.1% | |
| 50-75 years | 193 | 17.6% | 905 | 82.4% | |
| >75 years | 92 | 17.8% | 424 | 82.2% | |
| Hypertension | <0.001 | ||||
| No | 142 | 33.6% | 281 | 66.4% | |
| Yes | 226 | 16.7% | 1128 | 83.3% | |
| Diabetes mellitus | 0.002 | ||||
| No | 229 | 23.3% | 752 | 76.7% | |
| Yes | 139 | 17.5% | 657 | 82.5% | |
| Current cigarette smoking | <0.001 | ||||
| No | 282 | 18.4% | 1250 | 81.6% | |
| Yes | 86 | 35.2% | 158 | 64.8% | |
| Type of atrial fibrillation | <0.001 | ||||
| Paroxysmal | 229 | 34.0% | 444 | 66.0% | |
| Nonparoxysmal | 139 | 12.6% | 965 | 87.4% | |
| Patient enrollment setting | <0.001 | ||||
| Outpatient | 227 | 17.9% | 1044 | 82.1% | |
| Inpatient | 141 | 27.9% | 365 | 72.1% | |
| Chronic kidney disease | 0.440 | ||||
| No | 330 | 20.5% | 1282 | 79.5% | |
| Yes | 38 | 23.0% | 127 | 77.0% | |
| Stroke or systemic embolization | 0.009 | ||||
| No | 325 | 21.8% | 1165 | 78.2% | |
| Yes | 43 | 15.0% | 244 | 85.0% | |
| Left ventricular ejection fraction | 0.004 | ||||
| <40% | 29 | 13.4% | 187 | 86.6% | |
| ≥40% | 319 | 21.9% | 1137 | 78.1% | |
| Heart failure | 0.001 | ||||
| No | 265 | 22.8% | 895 | 77.2% | |
| Yes | 60 | 14.3% | 360 | 85.7% | |
| Ischemic heart disease | |||||
| No | 265 | 22.8% | 895 | 77.2% | |
| Yes | 44 | 21.5% | 161 | 78.5% | |
| Body mass index | 0.288 | ||||
| <25 | 79 | 21.6% | 287 | 78.4% | |
| ≥25 | 240 | 19.1% | 1018 | 80.9% | |
| CHA2DS2-VASc score | <0.001 | ||||
| <2 | 126 | 49.4% | 129 | 50.6% | |
| ≥2 | 242 | 15.9% | 1280 | 84.1% | |
| CHA2DS2-VASc | <0.001 | ||||
| <3 | 180 | 36.8% | 309 | 63.2% | |
| ≥3 | 188 | 14.6% | 1100 | 85.4% | |