Table 1.

Ravulizumab bodyweight-based dosage regimen

Bodyweight (kg)	Loading dosea (mg)	Maintenance doseb (mg)
≥ 5 to <10c	600	300
≥ 10 to <20	600	600
≥ 20 to <30	900	2100
≥ 30 to <40	1200	2700
≥ 40 to <60	2400	3000
≥ 60 to <100	2700	3300
≥ 100	3000	3600

The regimen used in clinical trials [19–21] and recommended in product information [13–15]

^aFor patients switching from eculizumab, administer 2 weeks after the last eculizumab infusion

^bStarting on day 15 and every 8 weeks thereafter in patients weighing ≥ 20 kg or every 4 weeks thereafter in those weighing < 20 kg

^cRavulizumab is not approved in the EU for patients weighing < 10 kg