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. 2021 Mar 14;16(4):597–607. doi: 10.1007/s11548-021-02334-z

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© The Author(s) 2021

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Fig. 7 — a Last contour of a tissue segment (contour of the tissue in the last slide where this tissue segment was visible) as 3D point cloud; b corresponding binary image, red line: points left after thinning, blue circle: center of the contour; c example of a dome added to a contour in 3D, red: top contour blue: added points for the dome