Table 2.

TADs affected by the complex rearrangement

TAD	Chromosome	Start	End	Length	BPJ	Inter-TAD BPJ	BP	Protein-coding genes	MIM morbid genes
tad71	chr4	70560001	71440000	879	4	4	4	17	2
tad72	chr4	71480001	72600000	1119	2	2	2	8	2
tad75	chr4	74040001	75080000	1039	2	2	2	15	2
tad82	chr4	79920001	81240000	1319	6	6	6	5	3
tad83	chr4	81280001	82280000	999	17	16	18	3	0
tad84	chr4	82320001	83240000	919	13	12	14	1	0
tad86	chr4	84520001	85480000	959	5	4	6	2	0
tad88	chr4	85960001	87240000	1279	16	14	18	2	0
tad89	chr4	87280001	88200000	919	22	22	22	6	0
tad90	chr4	88240001	89480000	1239	32	28	36	16	6
tad91	chr4	89520001	90040000	519	13	12	14	4	0
tad92	chr4	90080001	91240000	1159	33	28	38	4	1
tad23	chr7	19800001	20720000	919	2	2	2	4	0
tad59	chr7	48240001	49120000	879	2	2	2	1	0
tad20	chr11	20520001	21480000	959	2	2	2	3	1
tad27	chr11	26320001	26640000	319	2	2	2	2	1
tad32	chr11	30280001	31080000	799	2	2	2	3	0
tad30	chr19	28080001	29320000	1239	2	2	2	0	0
tad32	chr19	30080001	31200000	1119	2	2	2	6	1
tad35	chr19	32880001	32960000	79	2	2	2	1	0
tad6	chr21	19800001	20680000	879	8	8	8	0	0
tad7	chr21	20720001	22360000	1639	39	36	42	0	0
tad8	chr21	22400001	23360000	959	6	6	6	1	0
tad13	chr21	27000001	28160000	1159	6	6	6	5	2
tad14	chr21	28200001	29080000	879	6	4	8	2	0
tad137	chrX	137200001	137840000	639	2	2	2	1	0
tad141	chrX	141320001	142560000	1239	2	2	2	1	0

TAD topologically associated domain, BPJ breakpoint junction, BP breakpoint, MIM Mendelian Inheritance in Man