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. Author manuscript; available in PMC: 2021 Apr 17.
Published in final edited form as: Nat Med. 2021 Feb 22:10.1038/s41591-021-01256-2. doi: 10.1038/s41591-021-01256-2

Extended Data Fig. 7 |.

Extended Data Fig. 7 |

a, Abundance of ShA9 lantibiotic-α mRNA recovered by skin swabs from lesional skin at indicated time points for subjects treated with ShA9 or vehicle. Data represent Mean ± 95% confidence interval (ShA9: n = 35; Vehicle: n = 17 independent subjects). A linear mixed-model approach was used to take into account the repeated aspect of the trial (a). b-c, Correlation between abundance of ShA9 lantibiotic-α mRNA (b) or ShA9 AIP mRNA (c) and S. hominis DNA on the lesional skin of subjects with ShA9 at indicated time points. Statistical analysis for correlation was carried out by t distribution. Dotted line represents detection limit of the assay. Statistical analysis for correlation was carried out by two-tailed t distribution (n = 35 independent subjects) (b,c).