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. Author manuscript; available in PMC: 2022 Apr 1.
Published in final edited form as: Biochem Pharmacol. 2021 Feb 10;186:114462. doi: 10.1016/j.bcp.2021.114462

Figure 2.

Figure 2.

Flavones and CDK9 inhibitors suppress HIV replication in PBMCs. (A) Effects of compounds after 6 days’ incubation on HIV-1NL4.3 replication in infected PBMC cultures, as measured by supernatant p24Gag levels. (B) Effects of compounds after 6 days’ incubation on cell viability in uninfected PBMCs, as measured using Viacount dye. For A and B, results are presented relative to PBMCs treated with 0.1% DMSO and generated from 3 independent donors. Horizontal dotted lines denote activities at 100 and 50% of cells treated with 0.1% DMSO.