Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Effects of flavonoids and CDK9 inhibitors on active HIV replication and cell viability in PBMCs.
| Compound | EC50 (μM) | CC50 (μM) | Selectivity Index (CC50/EC50) |
|---|---|---|---|
| Chrysin | 9.2 ± 2.9 | > 30 | > 3.3 |
| Apigenin | 5.0 ± 1.6 | 19.8 ± 6.5 | 4.0 |
| Luteolin | 12.7 ± 3.2 | 13.9 ± 5.9 | 1.1 |
| L7G | 2.6 ± 0.8 | 18.3 ± 2.5 | 7.0 |
| Naringenin | > 30 | > 30 | n.d. |
| Flavopiridol | 0.020 ± 0.003 | 0.22 ± 0.04 | 11.0 |
| Atuveciclib | 3.4 ± 0.67 | 24.4 ± 1.5 | 7.2 |
