Figure 3. Population-associated alterations of N- and O-glycan compositions.
Statistically significant differences between (A) resident and elicited/M0 macrophage O-glycans, (B) resident and M0 macrophage N-glycans, (C) elicited/polarized macrophage O-glycans, and (D) M1, M2a, and M2c macrophage N-glycans. Data are represented as mean ± SD (n = 3) and are ordered by increasing mass (left to right). p values were determined using a one-way ANOVA with post-hoc Holm-Sidak comparisons of all pairs. *p < 0.05, **p < 0.01, ***p < 0.001; ND, not detected. Glycan representations follow symbol nomenclature.
(E) Putative structures of O-glycans identified in macrophage sub-populations using CORA or β-elimination. See also Figure S5 and Table S1.