Table 4.
The association between dynamic changes in the serum levels of CRP, IL-6, IL-10, 1L-18, SDC-1, and Vitamin D with death in patients with COVID-19.
| Death |
|||||
|---|---|---|---|---|---|
| Variable | N | Overall, N = 120a | Negative, N = 110a | Positive, N = 10a | p-valueb |
| CRP_T1 | 120 | 98 (84, 124) | 92 (82, 120) | 202 (189, 225) | <0.001 |
| CRP_T2 | 120 | 42 (34, 48) | 42 (33, 46) | 143 (126, 145) | <0.001 |
| CRP_T3 | 120 | 21 (17, 26) | 21 (17, 24) | 70 (59, 78) | <0.001 |
| IL6_T1 | 120 | 76 (65, 100) | 74 (64, 90) | 210 (192, 264) | <0.001 |
| IL6_T2 | 120 | 102 (88, 134) | 100 (87, 123) | 204 (190, 252) | <0.001 |
| IL6_T3 | 120 | 38 (32, 46) | 37 (32, 44) | 274 (247, 321) | <0.001 |
| IL18_T1 | 120 | 158 (140, 187) | 156 (139, 174) | 349 (342, 359) | <0.001 |
| IL18_T2 | 120 | 230 (189, 284) | 221 (187, 278) | 489 (465, 536) | <0.001 |
| IL18_T3 | 120 | 108 (90, 122) | 102 (90, 116) | 206 (197, 234) | <0.001 |
| VitD_T1 | 120 | 18 (13, 21) | 18 (14, 23) | 10 (8, 12) | <0.001 |
| VitD_T2 | 120 | 19 (15, 21) | 19 (16, 22) | 12 (8, 15) | <0.001 |
| VitD_T3 | 120 | 21 (16, 22) | 21 (17, 23) | 14 (7, 16) | <0.001 |
| IL10_T1 | 120 | 5 (4, 6) | 5 (4, 6) | 22 (10, 24) | <0.001 |
| IL10_T2 | 120 | 10 (7, 19) | 10 (7, 17) | 48 (29, 55) | <0.001 |
| IL10_T3 | 120 | 8 (6, 12) | 8 (6, 11) | 22 (11, 27) | 0.001 |
| Syndecan_T1 120 | 73 (63, 81) | 71 (62, 79) | 116 (85, 127) | <0.001 | |
| Syndecan_T2 120 | 88 (78, 93) | 87 (78, 92) | 148 (101, 164) | <0.001 | |
| Syndecan_T3 120 | 61 (53, 69) | 61 (52, 67) | 85 (77, 91) | <0.001 | |
a
Median (IQR).
b
Wilcoxon rank sum test.