Table 2.
Laboratory findings of acute severe and critically ill COVID-19 patients and convalescent cases.
| Normal range | Severe and critically ill n = 20 |
Convalescent n = 16 |
P | |
|---|---|---|---|---|
| Blood routine tests | ||||
| WBC count (109 cells/L) | 4.0–10.0 | 7.76 ± 3.73 | 6.46 ± 1.79 | 0.180 |
| Neutrophil (109 cells/L) | 1.8–8.0 | 6.58 ± 3.73 | 3.96 ± 1.20 | 0.007 |
| Lymphocyte (109 cells/L) | 0.9–5.2 | 0.65 ± 0.32 | 1.77 ± 0.68 | <0.001 |
| Monocyte (109 cells/L) | 0.16–1.0 | 0.44 ± 0.27 | 0.54 ± 0.18 | 0.211 |
| Eosinophil (109 cells/L) | 0.05–0.3 | 0.07 ± 0.09 | 0.15 ± 0.11 | 0.020 |
| HGB (g/L) | 110–150 | 106.30 ± 19.96 | 120.31 ± 20.91 | 0.048 |
| PLT (109 /L) | 100–400 | 196.55 ± 90.19 | 224.16 ± 43.69 | 0.239 |
| Blood coagulation tests | ||||
| Prothrombin time, s | 11.0–14.5 | 14.52 ± 1.31 | 13.63 ± 0.79 | 0.016 |
| Activated partial thromboplastin time, s | 28–42.8 | 41.60 ± 6.61 | 38.23 ± 3.13 | 0.054 |
| D-dimer, ng/mL | 68–494 | 3533.20 ± 3386.12 | 508.06 ± 356.06 | 0.001 |
| Fibrinogen,g/L | 2.0–4.0 | 5.14 ± 1.35 | 3.43 ± 0.94 | <0.001 |
| Clinical immunology | ||||
| Complement 3 (g/L) | 0.9–1.5 | 0.89 ± 0.32 | 1.04 ± 0.16 | 0.184 |
| Complement 4 (g/L) | 0.2–0.4 | 0.21 ± 0.09 | 0.25 ± 0.08 | 0.267 |
| IgA (g/L) | 0.7–5.0 | 2.46 ± 1.21 | 2.28 ± 0.79 | 0.680 |
| IgG (g/L) | 6.0–16.0 | 13.25 ± 3.12 | 13.80 ± 2.67 | 0.638 |
| IgM (g/L) | 0.6–2.0 | 1.10 ± 0.61 | 0.81 ± 0.25 | 0.160 |
| Liver function | ||||
| Alanine aminotransferase (U/L) | 5–40 | 49.78 ± 46.43 | 45.24 ± 59.02 | 0.801 |
| Aspartate aminotransferase (U/L) | 5–40 | 52.16 ± 38.14 | 40.20 ± 54.29 | 0.449 |
| Total protein, g/L | 65–85 | 62.45 ± 5.98 | 69.56 ± 5.722 | 0.001 |
| Albumin, g/L | 35–55 | 35.51 ± 4.54 | 41.67 ± 4.15 | <0.001 |
| Total bilirubin, μmol/L | 1.7–22.2 | 15.98 ± 11.24 | 11.34 ± 3.83 | 0.125 |
| Direct bilirubin, μmol/L | 0.0–6.0 | 5.08 ± 5.86 | 2.11 ± 0.73 | 0.042 |
| Cardiac function | ||||
| Troponin I, μg/L | 0.0–0.04 | 0.14 ± 0.52 | 0.01 ± 0.01 | 0.330 |
| Creatine kinase-MB (U/L) | 3–25 | 10.35 ± 9.53 | 8.07 ± 3.80 | 0.388 |
| Renal function | ||||
| Serum glucose, mmol/L | 3.9–6.1 | 8.68 ± 2.24 | 5.67 ± 1.27 | <0.001 |
| BUN (mmol/L) | 2.9–7.2 | 8.48 ± 5.31 | 5.85 ± 3.19 | 0.075 |
| Creatinine (μmol/L) | 44.0–133.0 | 76.85 ± 30.26 | 75.19 ± 16.80 | 0.845 |
| Arterial blood gases | ||||
| pH | 7.35–7.45 | 7.41 ± 0.05 | 7.41 ± 0.02 | 0.376 |
| Paco2, mm Hg | 35.0–48.0 | 44.92 ± 6.19 | 41.86 ± 4.90 | 0.132 |
| Pao2, mm Hg | 83.0–108.0 | 110.43 ± 31.97 | 106.79 ± 32.99 | 0.691 |
| Oxygen saturation (%) | 95–99% | 96.05 ± 9.45 | 97.74 ± 1.28 | 0.512 |