Table 4.
Microbiology of Candida Empyema
| Microbiology | Percent (n/n) |
|---|---|
| Candida species | |
| Candida albicans | 65% (53/81) |
| Candida glabrata | 26% (21/81) |
| Candida parapsilosis | 11% (9/81) |
| Candida tropicalis | 4% (3/81) |
| Candida krusei | 2% (2/81) |
| Candida dubliniensis | 1% (1/81) |
| More than 1 Candida speciesa | 10% (8/81) |
| Concurrent bacteria in pleural spaceb | 51% (41/81) |
| Bloodstream Infectionsc | |
| Candidemia | 2% (1/52) |
| Bacteremia | 8% (4/52) |
aAn additional patient was coinfected with Saccharomyces cerevisiae.
bThirty-one percent of patients (25 of 81) had more than 1 bacterial species. Gram-positive organisms accounted for 71% (29 of 41) of bacterial isolates; 20% (8 of 41) and 17% (7 of 41) of bacteria were Lactobacillus and obligate anaerobes, respectively.
cFifty-two patients had blood cultures performed within 7 days of Candida empyema.
NOTE: Note that only 4 C albicans isolates from pleural fluid of 4 patients were tested for antifungal susceptibility in vitro. Each isolate was susceptible to fluconazole and echinocandins.