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. 2021 Apr 17;188:114564. doi: 10.1016/j.bcp.2021.114564

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Fig. 2 — Pelargonidin reduces the severity of TNBS colitis in a dose-dependent manner. Colitis was induced by TNBS. After induction of colitis the mice were treated daily with Pelargonidin (1, 5 or 10 mg/Kg) or vehicle. Disease was monitored by daily evaluation of (A) changes in colitis disease activity index (CDAI) and by evaluation of the (B) Area Under the Curve (AUC). At the end of the experiment, we evaluated (C) colon length (cm) and (D) ratio of colon weight/colon length (g/cm). (E) Area of ulcers and (F) H&E staining of colon sections (10× magnification) and Histological Score from each experimental group. Results are expressed as mean ± SEM (n = 5–7); In graph A # TNBS Vs NT; * TNBS + Pel Vs TNBS; in all graphs # and * p < 0.05.