Table 3.

Mean increase in serum sodium (sNa) at 24 and 48 h after admission according to treatment and symptom severity.

	n	Mean change in serum sodium (mEq/L)		Mean serum sodium (mEq/L)
		At 24 h	At 48 h	Baseline	At 24 h	At 48 h
Whole cohort	62	8 ± 5	11 ± 9	118 ± 7†‡	124 ± 6§	128 ± 5
Hypertonic saline group	36	9 ± 5	12 ± 9	116 ± 7†‡*	123 ± 6§	127 ± 6
Conventional treatment group	26	6 ± 4	9 ± 8	121 ± 6†‡	126 ± 5	129 ± 4
Moderate symptoms	33	5 ± 4**	7 ± 7**	121 ± 5†‡	125 ± 4	127 ± 5
Severe symptoms	29	10 ± 4	14 ± 9	115 ± 7†‡	123 ± 7§	128 ± 5
sNa at admission, mEq/L
<120	30	10 ± 4***	16 ± 7***	113 ± 5†‡	121 ± 5§	127 ± 5
≥120	32	5 ± 4	5 ± 6	124 ± 3†‡	128 ± 4	128 ± 5

^†P < 0.05 baseline compared to 24h; ^‡P < 0.05 baseline compared to 48 h; ^§P < 0.05 24 h compared to 48 h; *P < 0.05 hypertonic saline group compared to conventional treatment group; **P < 0.05 moderate symptoms compared to severe symptoms; ***P < 0.05 admission sNa < 120 mEq/L compared to admission sNa ≥ 120 mEq/L.