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. 2021 Jan 25;249(1):1–18. doi: 10.1530/JOE-20-0398

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© 2021 The authors

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Apelin relived early inflammatory response in heart of diabetic mice. (A) Representative images of immunohistochemistry for CD68, mac-2 and E-cadherin in heart sections from C57 and diabetic mice with or without apelin/F13A treatment as quantified in (B, C and D) (CD68: diabetes (P = 0.001), treatment (P = 0.000), interaction (P = 0.578); mac-2: diabetes (P = 0.263), treatment (P = 0.002), interaction (P = 0.054); E-cadherin diabetes (P = 0.000), treatment (P = 0.000), interaction (P = 0.000); n = 6 mice per group, *P < 0.05). Scale bars represent 50 μm.