Figure 5.

Apelin decreased adhesion molecules in heart of diabetic mice. (A) Representative images of immunohistochemistry for VCAM-1 and ICAM-1 in heart sections from C57 and diabetic mice with or without apelin/F13A treatment as quantified in (B and C) (VCAM-1: diabetes (P = 0.000), treatment (P = 0.000), interaction (P = 0.000); ICAM-1: diabetes (P = 0.000), treatment (P = 0.000), interaction (P = 0.000); n= 6 mice per group, *P < 0.05). Scale bars represent 50 μm.