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. 2021 Apr 17;21:360. doi: 10.1186/s12879-021-06061-3

Table 1.

Sensitivity of pooling methods

Pooling methods Standard method (individual samples) Sensitivity (%) (95% CI) False negative (%)
Positive Negative
4-fold pooling
 Positive 30 0 75 (61.7–88.3) 25
 Negative 10 0
8-fold pooling
 Positive 25 0 62.5 (47.5–77.5) 37.5
 Negative 15 0
4-fold pooling of weak positive samples
 Positive 10 0 50 (28.09–71.91) 50
 Negative 10 0
8-fold pooling of weak positive samples
 Positive 5 0 2 (6.03–43.97) 75
 Negative 15 0