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. 2021 Feb 10;10(3):316–324. doi: 10.1530/EC-21-0026

Table 4.

Percentage of patients in each diagnostic group reporting an improvement greater than the individual-level minimal important change, 6 weeks after treatment initiation.

ThyPRO scale Non-toxic goiter Toxic nodular goiter Graves’ hyperthyroidism Graves’ orbitopathy Autoimmune hypothyroidism Other thyroid diagnoses
Goiter symptoms 54 33 28 35 21 40
Hyperthyroid symptoms 25 23 63 53 21 36
Hypothyroid symptoms 11 16 25 14 13 7
Eye symptoms 15 26 17 35 13 27
Cognition 30 29 36 41 29 13
Tiredness 30 33 49 53 42 47
Anxiety 41 37 50 53 23 13
Depressivity 31 29 31 53 30 13
Emotional susceptibility 36 30 43 53 31 20
Impaired daily life 22 30 47 47 31 47
Impaired social life 14 14 17 35 19 13
Impaired sex life 20 25 28 20 34 36
Cosmetic complaints 15 11 17 13 13 7
ThyPRO composite QoL 40 35 49 53 36 27