Table 2.
Maternal Frailty (MaFra) Inventory. Intrauterine and extrauterine preterm birth risk factors included in the MaFra Inventory. 150 items assess the 71 listed factors while 24 Items collect more general sociodemographic, anamnestic and basic pregnancy history information for a total of 174 items included in the MaFra Inventory
| System | Pregnancy anamnesis | Factors | Number of items | High/ low risk | Uterine environment | Study |
|---|---|---|---|---|---|---|
| UTERINE | PREVIOUS (Conditions of Pregnancy) | Parity | 1 | L | U | [34] |
| UTERINE | PREVIOUS (Conditions of Pregnancy) | Delivery Onset | 2 | L | U | [35] |
| UTERINE | PREVIOUS (Conditions of Pregnancy) | Breastfeeding | 1 | L | U | [36] |
| UTERINE | PREVIOUS (Conditions of Pregnancy) | Multiple Gestation | 1 | L | U | [37] |
| UTERINE | PREVIOUS (Conditions of Pregnancy) | Voluntary Interruption of Pregnancy | 1 | L | U | [38] |
| UTERINE | PREVIOUS (Conditions of Pregnancy) | Miscarriage | 1 | L | U | [38] |
| UTERINE | PREVIOUS (Conditions of Pregnancy) | Prior PTB | 2 | H | U | [4] |
| UTERINE | CURRENT (Conditions of Pregnancy) | Fetal Growth Restriction | 9 | H | F | [9] |
| UTERINE | CURRENT (Conditions of Pregnancy) | Medically Assisted Procreation | 2 | H | U | [22] |
| UTERINE | CURRENT (Conditions of Pregnancy) | Short Cervical Length | 1 | H | U | [19] |
| UTERINE | CURRENT (Conditions of Pregnancy) | Placenta Previa | 1 | H | P | [24] |
| UTERINE | CURRENT (Conditions of Pregnancy) | Placental Abruption | 1 | H | P | [5] |
| UTERINE | CURRENT (Conditions of Pregnancy) | Uterine Fibroid (Leiomyomas) | 1 | L | U | [39] |
| UTERINE | CURRENT (Conditions of Pregnancy) | Polidramnios | 1 | H | U | [20] |
| UTERINE | CURRENT (Conditions of Pregnancy) | Oligoidramnios | 1 | L | U | [40] |
| UTERINE | CURRENT (Conditions of Pregnancy) | Fetal Fibronectin | 1 | H | F | [41] |
| UTERINE | CURRENT (Conditions of Pregnancy) | Interleukin (IL)-6-Inflammatory Cytokine | 1 | H | U | [42] |
| UTERINE | CURRENT (Conditions of Pregnancy) | Fetal Sex | 1 | L | F | [43] |
| UTERINE | CURRENT (Conditions of Pregnancy) | Pregnancy Induced Hypertension (PIH) | 1 | H | P | [44] |
| UTERINE | CURRENT (Conditions of Pregnancy) | Preeclampsia | 3 | H | P | [45] |
| EXTRAUTERINE | CURRENT (Conditions of Pregnancy) | Pregnancy Awareness | 10 | L | - | [46] |
| EXTRAUTERINE | CURRENT (Conditions of Pregnancy) | Obesity | 4 | L | - | [47] |
| EXTRAUTERINE | CURRENT (Conditions of Pregnancy) | Gestational Diabetes | 2 | L | - | [48] |
| EXTRAUTERINE | CURRENT (Conditions of Pregnancy) | Thyroid Disease | 2 | L | - | [49] |
| EXTRAUTERINE | CURRENT (Conditions of Pregnancy) | Autoimmune Syndrome | 1 | H | - | [27] |
| EXTRAUTERINE | CURRENT (Conditions of Pregnancy) | Urinary Tract Infection (UTI) | 1 | H | - | [26] |
| EXTRAUTERINE | CURRENT (Conditions of Pregnancy) | Fever | 1 | L | - | [50] |
| EXTRAUTERINE | CURRENT (Conditions of Pregnancy) | Rubella | 1 | L | - | [51] |
| EXTRAUTERINE | CURRENT (Conditions of Pregnancy) | Infection | 4 | L | - | [52] |