Table 2.

Maternal Frailty (MaFra) Inventory. Intrauterine and extrauterine preterm birth risk factors included in the MaFra Inventory. 150 items assess the 71 listed factors while 24 Items collect more general sociodemographic, anamnestic and basic pregnancy history information for a total of 174 items included in the MaFra Inventory (Continued)

System	Pregnancy anamnesis	Factors	Number of items	High/ low risk	Uterine environment	Study
EXTRAUTERINE	CURRENT (Conditions of Pregnancy)	Corticosteroids	4	L	-	[53]
EXTRAUTERINE	CURRENT (Conditions of Pregnancy)	Analgesics	1	L	-	[54]
EXTRAUTERINE	CURRENT (Conditions of Pregnancy)	Antihypertensives	1	L	-	[55]
EXTRAUTERINE	CURRENT (Conditions of Pregnancy)	Antiemetics	1	L	-	[56]
EXTRAUTERINE	CURRENT (Conditions of Pregnancy)	Antihistamines	1	L	-	[57]
EXTRAUTERINE	CURRENT (Conditions of Pregnancy)	Anti-inflammatories	1	L	-	[58]
EXTRAUTERINE	CURRENT (Conditions of Pregnancy)	Hormones	1	L	-	[59]
EXTRAUTERINE	CURRENT (Conditions of Pregnancy)	Vaccinations	1	L	-	[60]
EXTRAUTERINE	CURRENT (Conditions of Pregnancy)	Antibiotics	1	L	-	[61]
EXTRAUTERINE	BEFORE (Lifestyle)	Folic Acid Supplementation	3	L	-	[62]
EXTRAUTERINE	BEFORE (Lifestyle)	Estroprogestinic Therapy	1	L	-	[63]
EXTRAUTERINE	BEFORE (Lifestyle)	Diabetes	1	L	-	[64]
EXTRAUTERINE	BEFORE (Lifestyle)	Hypertension	1	L	-	[64]
EXTRAUTERINE	BEFORE (Lifestyle)	Maternal Medication	2	L	-	[65]
EXTRAUTERINE	BEFORE (Lifestyle)	Cigarette Smoking	2	L	-	[7]
EXTRAUTERINE	BEFORE (Lifestyle)	Alcohol use	2	L	-	[66]
EXTRAUTERINE	BEFORE (Lifestyle)	Use of Drugs/Substance Abuse	6	L	-	[67]
EXTRAUTERINE	BEFORE (Lifestyle)	Caffeine	2	L	-	[68]
EXTRAUTERINE	BEFORE (Lifestyle)	Maternal Stress	1	L	-	[69]
EXTRAUTERINE	BEFORE (Lifestyle)	Weight	1	L	-	[70]