Table 1.
Relationship to infectious and kidney diseases related to co-DEGs based on the CTD database
| Genes | Disease name | Disease ID | Inference score | Reference count |
|---|---|---|---|---|
| VMP1 | Proteus Infections | MESH:D011512 | 7.77 | 2 |
| Acinetobacter Infections | MESH:D000151 | 4 | 1 | |
| Bacterial Infections | MESH:D001424 | 3.79 | 1 | |
| Kidney Diseases | MESH:D007674 | 74.98 | 274 | |
| Acute Kidney Injury | MESH:D058186 | 57.3 | 164 | |
| Kidney Tubular Necrosis, Acute | MESH:D007683 | 37.19 | 38 | |
| SLPI | Bacterial Infections | MESH:D001424 | 14.92 | 8 |
| Pneumonia, Pneumocystis | MESH:D011020 | 12.12 | 4 | |
| Staphylococcal Infections | MESH:D013203 | 11.08 | 31 | |
| Kidney Diseases | MESH:D007674 | 140.73 | 445 | |
| Acute Kidney Injury | MESH:D058186 | 81.18 | 300 | |
| Proteinuria | MESH:D011507 | 72.69 | 160 | |
| PTX3 | Bacterial Infections | MESH:D001424 | 10.56 | 4 |
| Helicobacter Infections | MESH:D016481 | 9.69 | 3 | |
| Pseudomonas Infections | MESH:D011552 | 6.47 | 2 | |
| Kidney Diseases | MESH:D007674 | 107.5 | 348 | |
| Acute Kidney Injury | MESH:D058186 | 88.8 | 205 | |
| Proteinuria | MESH:D011507 | 83.53 | 150 | |
| TIMP1 | Bacterial Infections | MESH:D001424 | 38.56 | 11 |
| IMMUNE SUPPRESSION | OMIM:146850 | 25.12 | 4 | |
| Staphylococcal Infections | MESH:D013203 | 24.54 | 114 | |
| Glomerulonephritis, IGAa | MESH:D005922 | 11.38 | 6 | |
| Kidney Diseases | MESH:D007674 | 417.32 | 804 | |
| Acute Kidney Injury | MESH:D058186 | 305.13 | 549 | |
| Proteinuria | MESH:D011507 | 245.56 | 439 | |
| OLFM4 | IMMUNE SUPPRESSION | OMIM:146850 | 4.94 | 1 |
| Hidradenitis Suppurativa | MESH:D017497 | 3.98 | 1 | |
| Meningitis, Pneumococcal | MESH:D008586 | 3.65 | 1 | |
| Kidney Diseases | MESH:D007674 | 52.19 | 67 | |
| Acute Kidney Injury | MESH:D058186 | 33.22 | 21 | |
| Proteinuria | MESH:D011507 | 31.39 | 24 | |
| LCN2 | Meningitis, Cryptococcal | MESH:D016919 | 32.23 | 13 |
| Mycoses | MESH:D009181 | 30.46 | 30 | |
| Candidiasis, Vulvovaginal | MESH:D002181 | 22.19 | 5 | |
| Kidney Diseasesa | MESH:D007674 | 328.81 | 776 | |
| Acute Kidney Injurya | MESH:D058186 | 227.05 | 523 | |
| Proteinuria | MESH:D011507 | 177.1 | 385 | |
| Renal Insufficiency | MESH:D051437 | 140.84 | 170 | |
| S100A9 | Bacterial Infections | MESH:D001424 | 22.04 | 8 |
| Staphylococcal Infections | MESH:D013203 | 18.13 | 15 | |
| IMMUNE SUPPRESSION | OMIM:146850 | 17.92 | 4 | |
| Kidney Diseases | MESH:D007674 | 274.34 | 537 | |
| Acute Kidney Injury | MESH:D058186 | 214.94 | 463 | |
| Renal Insufficiency | MESH:D051437 | 146.23 | 153 |
aDirect evidence of marker or mechanism in this disease