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. Author manuscript; available in PMC: 2022 Mar 11.
Published in final edited form as: J Med Chem. 2021 Feb 17;64(5):2777–2800. doi: 10.1021/acs.jmedchem.0c02070

Table 10.

Antiviral EC68 (μM) against ZIKV-FLR in U87 cells.

ZVpro IC50 (μM) ZIKV-FLR EC68 (μM)
1 21.7 >10
50 0.76 >10
7 3.1 5.0
102 1.0 3
79 1.1 2.5
55 1.1 2.5
46 0.71 2.5
69 0.79 1.2
59 0.68 1.2
62 0.53 1.2
66 0.40 1.2
78 0.24 1.2
103 0.13 0.6
47 0.20 0.3–0.6