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Structures and inhibitory activities of compounds 59–72.a
 | ||||
|---|---|---|---|---|
| Compd. | R2 | R5 | R6 | IC50 (μM) |
| 59 |  |
 |
 |
0.68 |
| 60 |  |
 |
 |
3.3 |
| 61 |  |
 |
 |
1.8 |
| 62 |  |
 |
 |
0.53 |
| 63 |  |
 |
 |
6.1 |
| 64 |  |
 |
 |
1.8 |
| 65 |  |
 |
 |
1.3 |
| 66 |  |
 |
 |
0.40 |
| 67 |  |
 |
 |
2.3 |
| 68 |  |
 |
 |
5.3 |
| 69 |  |
 |
 |
0.79 |
| 70 |  |
 |
 |
1.1 |
| 71 |  |
 |
 |
18.5 |
| 72 |  |
 |
 |
4.7 |
Standard errors of all IC50 values are less than 30%.
