Table 1.
Characteristics of BEACON GWAS study participants
| Controls (n = 3207) | BE cases (n = 3295) | EAC cases (n = 2515) | ||||
|---|---|---|---|---|---|---|
| N | % | N | % | N | % | |
| Age (years) | ||||||
| <50 | 726 | 22.6 | 449 | 13.7 | 189 | 7.6 |
| 50–59 | 885 | 27.6 | 780 | 23.7 | 547 | 21.9 |
| 60–69 | 963 | 30.0 | 1011 | 30.7 | 884 | 35.4 |
| 70+ | 633 | 19.8 | 1048 | 31.9 | 875 | 35.1 |
| Sex | ||||||
| Female | 880 | 27.4 | 806 | 24.5 | 320 | 12.7 |
| Male | 2327 | 72.6 | 2489 | 75.5 | 2195 | 87.3 |
| BMI | ||||||
| <25 | 786 | 36.3 | 608 | 22.2 | 245 | 24.6 |
| 25–29.99 | 944 | 43.6 | 1191 | 43.6 | 455 | 45.7 |
| 30–34.99 | 307 | 14.2 | 657 | 24.0 | 201 | 20.2 |
| 35+ | 130 | 6.0 | 278 | 10.2 | 95 | 9.5 |
| Smoking status | ||||||
| No | 889 | 40.9 | 1081 | 35.2 | 568 | 25.2 |
| Yes | 1284 | 59.1 | 1994 | 64.8 | 1686 | 74.8 |
| Smoking pack-years | ||||||
| None | 889 | 41.3 | 1081 | 43.6 | 568 | 30.1 |
| <15 | 358 | 16.6 | 465 | 18.8 | 319 | 16.9 |
| 15–29 | 326 | 15.1 | 348 | 14.0 | 357 | 18.9 |
| 30–44 | 273 | 12.7 | 279 | 11.3 | 308 | 16.3 |
| 45+ | 309 | 14.3 | 306 | 12.3 | 335 | 17.8 |
| Regular NSAID use | ||||||
| Never | 814 | 44.0 | 1050 | 57.7 | 559 | 33.0 |
| Ever | 1038 | 56.0 | 770 | 42.3 | 1133 | 67.0 |
| Weekly reflux/heartburn | ||||||
| No | 1448 | 80.6 | 1058 | 47.2 | 965 | 53.0 |
| Yes | 349 | 19.4 | 1186 | 52.8 | 854 | 47.0 |
Numbers may not add to total due to missing data. NSAID, non-steroidal anti-inflammatory drug.