Table 4.
Assessment of gene-level associations with risk of BE using GWAS meta-analysis data via application of MAGMA
Gene | Chr | SNPsa | P valueb | FDR qc | |
---|---|---|---|---|---|
1 | GHR | 5 | 882 | 0.0097 | 0.071 |
2 | IGFBP3 | 7 | 37 | 0.0135 | 0.071 |
3 | IGF1R | 15 | 1226 | 0.0176 | 0.071 |
4 | GH1 | 17 | 27 | 0.09 | 0.26 |
5 | IGFBP1 | 7 | 29 | 0.11 | 0.27 |
6 | IGFBP4 | 17 | 51 | 0.22 | 0.44 |
7 | IGF2 | 11 | 84 | 0.48 | 0.72 |
8 | IGFBP5 | 2 | 87 | 0.48 | 0.72 |
9 | IGF1 | 12 | 223 | 0.70 | 0.88 |
10 | IGFBP6 | 12 | 18 | 0.83 | 0.88 |
11 | IGFALS | 16 | 58 | 0.87 | 0.88 |
12 | IGFBP2 | 2 | 99 | 0.88 | 0.88 |
aNumber of SNPs per gene.
bGene-level P value.
cFalse discovery rate q value.