Figure 1. General in vitro evaluation scenarios (S1–S3) of LF capacity against virus.

Each scenario has a specific incubation time. These in vitro evaluation scenarios are used in studies of HCV, SARS-CoV-2, and many other viruses. They can be used to analyze the antiviral activities over different cell lines and/or experimental conditions. (A) S1 is the protection scenario to evaluate the protective capacity of any antiviral agent. (B) S2 is the neutralizing scenario, which is applied for evaluation of the neutralizing potential of any antiviral agent. (C) S3 is the treatment scenario used in evaluation of the therapeutic capacity of any antiviral agent.