Table 2.
Hemostatic parameters including control groups and depending on whether patients required hospital admission
| Parameter | Non-COVID-19 inpatients (n = 30) | Non-COVID-19 healthy individuals (n = 30) | COVID-19 inpatients (n = 50) | COVID-19 Outpatients (n = 102) | p-value |
|---|---|---|---|---|---|
| D-dimer (µg/mL) | 2.3 (0.4–1) | 0.61 (0.33–0.94) | 2.48 (0.88–6.86) | 0.4 (0.27–0.56) |
< 0.05* < 0.05** < 0.05*** 0.93**** < 0.05***** |
| Fibrinogen (mg/dL) | 468 (323–381) | 312 (210–250) | 511 (395–568) | 346.5 (291–374) |
< 0.05* < 0.05** < 0.05*** < 0.05**** < 0.05***** |
| ADAMTS13 activity (%) | 85.1 (68.5–107.6) | 99.9 (82.4–112.5) | 44.4 (32.5–60.8) | 59.9 (43.4–78.75) |
< 0.05* < 0.05** < 0.05*** < 0.05**** < 0.05***** |
| VWF antigen (%) | 211.2 (132.2–311.2) | 145.3 (103–176) | 337.8 (270.0–394.9) | 121.6 (95.75–151.95) |
< 0.05* < 0.05** < 0.05*** 0.19**** < 0.05***** |
| VWF antigen/ADAMTS13 activity ratio | 2.58 (1.46–3.99) | 1.41 (1.20–1.95) | 7.67 (4.67–13.68) | 2.11 (1.39–3.17) |
< 0.05* < 0.05** 0.25*** < 0.05**** < 0.05***** |
Data are expressed as median (p25–p75)
VWF antigen von Willebrand factor antigen
*p value: between COVID-19 inpatients and COVID-19 outpatients
**p value: between COVID-19 inpatients and non-COVID-19 inpatients
***p value: between COVID-19 outpatients and non-COVID-19 inpatients
****p value: between COVID-19 outpatients and non-COVID-19 healthy individuals
*****p value: between COVID-19 inpatients and non-COVID-19 healthy individuals