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. 2021 Mar 15;49(7):3981–3996. doi: 10.1093/nar/gkab149

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© The Author(s) 2021. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Figure 3. — The effect of antibiotic resistant genes (bla_CTX-M-55 or mcr-1) on the fitness of E. coli BW25113/pHN1122-1(A) and BW25113/pHNSHP45 (B). E. coli BW25113/pHNSHP45 and BW25113/pHN1122-1 were competed with E. coli BW25113/pHNSHP45Δmcr-1 and BW25113/pHN1122–1Δbla_CTX-M-55, respectively. All competitions assays were carried out with three biological replicates and last for 10 days. The relative fitness of each strain was detected every day (from D1 to D10). P-values were calculated by one-way ANOVA test.