Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Mar 30;49(7):4144–4154. doi: 10.1093/nar/gkab203

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2021. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

PMC Copyright notice

Figure 1. — (A) Apo-NP (PDB 2Q06) and the obligate monomeric NP-DL and DLDC2 shown in the same orientation. Three RNA nucleotides are modeled onto the body domain near the 74–88 loop. The proteins share highly similar tertiary folds demonstrating neither RNA binding nor tail-loop deletion distorts the overall structure. G1 residues (R74, R75, R174, R175), R65 and K87 are marked in blue in the structures. (B) 2F_o – F_c omit maps were generated for the nucleotides modeled on NP-DL (black: simple omit map; pink: simulated-annealing omit map) and contoured at 1σ as shown. (C) The RNA moieties on NP-DL and DLDC2 are situated in a cavity defined by R65, R74/75 and K87. The conformations of two RNA moieties do not deviate significantly. Protein cores are shown as ribbons (NP-DL: green; DLDC2: magenta). RNA is shown as cartoon in green (NP-DL/RNA) and pink (DLDC2/RNA).