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. 2021 Mar 21;49(7):3651–3660. doi: 10.1093/nar/gkab153

Graphical Abstract.

Graphical Abstract

Dynamic interplay of bubble, supercoil and twisted B-DNA with the Z-DNA state of CG or TG repeats detected by smFRET under various mechanical (force and σ) conditions imposed by magnetic tweezers. TG repeats exhibit higher B–Z transition rates (k) than CG repeats at their respective midpoint σ values.