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. 2020 Nov 2;70(5):1277–1289. doi: 10.1007/s00262-020-02750-1

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — Granzyme B in peripheral blood mononuclear cells (GrB-PBMC) in ovarian and lung tumors. a The expression of GrB-PBMC was compared between patients with nonmalignant lesions (ovarian tumors and leiomyomas), lung cancer, and ovarian cancer. b GrB-PBMC in ovarian and lung cancer depending on the stage of malignancy. Ovarian tumors were staged according to FIGO (International Federation of Gynecology and Obstetrics) system. Lung tumors were staged following the American Joint Committee on Cancer (AJCC) TNM system. c GrB-PBMC in ovarian cancer coexisting with PNS and without PNS. d GrB-PBMC in lung cancer coexisting with PNS and without PNS. e GrB-PBMC in lung cancer with and without onconeural antibodies. The central line corresponds to the median. The upper and lower “hinges” correspond to the first and third quartiles. P values are denoted as asterisks: ns—p > 0.05, *p < 0.05; **p < 0.01; ***p < 0.001, ****p < 0.0001. A statistical test is specified in the text