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. 2020 Nov 4;70(5):1365–1378. doi: 10.1007/s00262-020-02776-5

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — Kaplan–Meier survival curves according to infiltration of S100A8+ tumor cell (TC) and S100A8+ immune cell (IC) in invasive breast carcinoma. As a whole, presence of S100A8+ TC (a) and infiltration of S100A8+ IC (b) are associated with poor disease-specific survival. In hormone receptor (HR)-positive subgroup, S100A8+ TC (c) and S100A8+ IC (d) are also associated with decreased disease-specific survival. In HR-negative subgroup, there is no statistical difference in survival in relation to S100A8+ TC (e) or S100A8+ IC (f) infiltration