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. 2020 Nov 4;70(5):1365–1378. doi: 10.1007/s00262-020-02776-5

Fig. 6.

Fig. 6

Kaplan–Meier survival curves according to combination of S100A8+ immune cell (IC) and other IC subset infiltration in pre-invasive carcinoma. Solid line indicates S100A8+ IC (−) group and dotted line indicates S100A8+ IC (+) group. S100A8+ IC (+) group is associated with shorter ipsilateral breast recurrence-free survival compared to S100A8+ IC (−) group in the PD-L1+ IC (−) (a), CD8+ TIL-low (c), and FOXP3+ TIL-low (e) subgroups. No statistical difference in recurrence-free survival is observed between S100A8+ IC (+) and S100A8+ IC (−) groups in the PD-L1+ IC (+) (b), CD8+ TIL-high (d), and FOXP3+ TIL-high (f) subgroups