Fig. 5.

ΔNp63 binding causes H3K27ac of flanking nucleosomes. a Average chromatin architecture for H3K27ac at ΔNp63 ChIP-seq peaks centered on p63BS. Data are plotted for each H3K27ac ChIP-seq experiment from K562 + ΔNp63 and K562 + ΔNp63(R304W) control experiments. b H3K27ac at transcriptional start sites (TSS). c, d H3K27ac at two p63BS. Average H3K27ac from two replicate experiments for K562 + ΔNp63 and K562 + ΔNp63(R304W). Nucleosome occupancy as determined from MNase-seq from non-p63 expressing K562 [50]