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. 2021 Feb 4;92(5):534–541. doi: 10.1136/jnnp-2020-325456

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© Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.

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Expert-opinion-based approach for patient selection within the 4.5 hours time window. Decision for intravenous thrombolysis (IVT) should not delay thrombectomy (eg, direct thrombectomy or immediate transfer to a thrombectomy-capable centre recommended). AHA/ASA, American Heart/Stroke Association; APTT, activated partial thrombin time; DOAC, direct oral anticoagulant; ECT, ecarin clotting time; INR, international normalised ratio; MT, mechanical thrombectomy; PT, prothrombine time; TT, thrombin time; ULN, upper limit normal.