Table 2.

Liability-scale RA heritability h ² estimated from the tested genome-wide variants in each ancestry

Ancestry	All tested variants		Non-MHC variants*
	h 2	SE of h 2	h 2	SE of h 2	Proportion of h2 explained by
					Known RA loci	Novel RA loci
East Asian	0.176	0.053	0. 123	0. 012	43.0%	6.9%
European	0. 275	0.096	0. 185	0. 021	38.1%	1.8%

*The MHC region was defined as spanning as the 24–37 Mb region of chromosome 6 in hg19.

MHC, major histocompatibility complex; RA, rheumatoid arthritis.