Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Nov 18;80(5):651–659. doi: 10.1136/annrheumdis-2020-218881

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.

PMC Copyright notice

Comparison between the antigen-binding bead assay and conventional methods; ANA test and anti-CENP-B antibody by ELISA. (A) The numbers of antibodies with positivity in sera were plotted against the titres of anti-CENP-B antibody. Linear regression lines, the correlation coefficient, and p value of the regression line are shown. The dotted line indicates cut-off value by ELISA. (B) Number of individuals with and without bead assay positivity depending on various cut-off values. (C) Pie charts show positive rates for anti-CENP-B antibody by ELISA and the centromere antigen-binding bead assay. Having two or more antibodies against centromere antigens was considered as positive. Individuals who were additionally identified as ACA positive by the bead assay are shown by blue. ANA, anti-nuclear antibody; ELISA, enzyme-linked immunosorbent assay; HC, healthy controls.