Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Apr 13;14:1631–1645. doi: 10.2147/DMSO.S298950

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2021 Zuo et al.

This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).

PMC Copyright notice

The overexpression of NRF2 alleviated pyroptosis and OS, unable to interfere with the expression of MALAT1 and miR-200c. (A–C) The pyroptosis and OS levels of the NRF2 overexpression group were determined by WB and qRT-PCR. *P<0.05, **P<0.01, ***P<0.001, ****P<0.0001, ns, non significant. (D) GSH, SOD and MDA levels. *P<0.05, ns, non significant. (E and F) qRT-PCR was used to verify that NRF2 is a downstream factor cannot, incapable of interfering with the levels of MALAT1 and miR-200c. *P<0.05, **P<0.01, ns, non significant. I, HG+ control; II, HG + pcNDA-NC; III, HG + pcNDA-NRF2; IV, HG + pcNDA-NRF2 + AT; V, HG + miR-200c mimics + Si-NC; VI, HG + miR-200c mimics + Si-MALAT1; VII, HG + pcNDA-MALAT1+ inhibitor-NC;VIII, HG + pcNDA-MALAT1+ miR-200c inhibitor.