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. 2021 Apr 13;14:1631–1645. doi: 10.2147/DMSO.S298950

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© 2021 Zuo et al.

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AT acts to suppress pyroptosis and OS via MALAT1/miR-200c/NRF2 activity. (A–D) The effects of AT on pyroptosis and OS of the AT group after MALAT1 knockdown and miR-200c overexpression were assayed by Western blotting. *P <0.05, **P <0.01, ***P <0.001, ns, non significant. (E and F) Flow cytometry, (G and H) GSH, SOD and MDA levels. **P <0.01, ns, non significant. I, HG + control; II, HG + NC siRNA; III, HG + MALAT1 siRNA; IV, HG + MALAT1siRNA + AT; V, NG + control; VI, NG + mimics-NC; VII, NG + miR-200c mimics; VIII, NG + miR-200c mimics + AT.