Table 1. Clinical features of 50 brainstem gliomas in adult.
| Grade | Type (number) | Sex | Age (years) | Duration of symptoms (months) | KPS | Tumor epicenter | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Male | Female | ≥55 | <55 | ≥3 | <3 | ≥70 | <70 | Midbrain | Pons | Medulla | ||
| WHO IV | GBM (22) | 14 (63.6) | 8 (36.4) | 16 (72.7) | 6 (27.3) | 8 (36.4) | 14 (63.6) | 12 (54.5) | 10 (45.5) | 2 (9.1) | 18 (81.8) | 2 (9.1) |
| DMLG (4) | 3 (75.0) | 1 (25.0) | 3 (75.0) | 1 (25.0) | 2 (50.0) | 2 (50.0) | 2 (50.0) | 2 (50.0) | 2 (50.0) | 2 (50.0) | 0 (0) | |
| WHO III | AA (12) | 7 (58.3) | 5 (41.7) | 8 (66.7) | 4 (33.3) | 9 (75.0) | 3 (25.0) | 7 (58.3) | 5 (41.7) | 1 (8.3) | 10 (83.4) | 1 (8.3) |
| WHO II | DA (9) | 5 (55.6) | 4 (44.4) | 2 (22.2) | 7 (77.8) | 6 (66.7) | 3 (33.3) | 9 (100.0) | 0 (0) | 1 (11.1) | 8 (88.9) | 0 (0) |
| O (2) | 1 (50.0) | 1 (50.0) | 0 (0) | 2 (100.0) | 2 (100.0) | 0 (0) | 1 (50.0) | 1 (50.0) | 0 (0) | 2 (100.0) | 0 (0) | |
| WHO I | PA (1) | 1 (100.0) | 0 (0) | 0 (0) | 1 (100.0) | 1 (100.0) | 0 (0) | 1 (100.0) | 0 (0) | 1 (100.0) | 0 (0) | 0 (0) |
| Total, % | 62 | 38 | 58 | 42 | 56 | 44 | 64 | 36 | 14 | 80 | 6 | |
| Grade | Type (number) | Tumor enhancement | Diameter (cm) | Radiotherapy | Chemotherapy | Status | Median OS (months) | |||||
| Yes | No | ≥2 | <2 | Yes | No | Yes | No | Dead | Alive | |||
| WHO IV | GBM (22) | 14 (63.6) | 8 (36.4) | 10 (45.5) | 12 (54.5) | 22 (100.0) | 0 (0) | 22 (100.0) | 0 (0) | 21 (98.0) | 1 (2.0) | 9.5 |
| DMLG (4) | 2 (50.0) | 2 (50.0) | 2 (50.0) | 2 (50.0) | 4 (100.0) | 0 (0) | 4 (100.0) | 0 (0) | 4 (100.0) | 0 (0) | 7.5 | |
| WHO III | AA (12) | 6 (50.0) | 6 (50.0) | 3 (25.0) | 9 (75.0) | 12 (100.0) | 0 (0) | 12 (100.0) | 0 (0) | 10 (83.3) | 2 (16.7) | 17.5 |
| WHO II | DA (9) | 4 (45.4) | 5 (55.6) | 5 (55.6) | 4 (45.4) | 9 (100.0) | 0 (0) | 5 (55.6) | 4 (45.4) | 7 (77.8) | 2 (22.2) | 32.0 |
| O (2) | 0 (0) | 2 (100.0) | 2 (100.0) | 0 (0) | 2 (100.0) | 0 (0) | 1 (50.0) | 1 (50.0) | 1 (50.0) | 1 (50.0) | 37.0 | |
| WHO I | PA (1) | 0 (0) | 1 (100.0) | 0 (0) | 1 (100.0) | 1 (100.0) | 0 (0) | 0 (0) | 1 (100.0) | 0 (0) | 1 (100.0) | 38.0 |
| Total, % | 52 | 48 | 44 | 56 | 100 | 0 | 88 | 12 | 86 | 14 | ||
Data are presented as n (%).
AA: anaplastic astrocytoma, DA: diffuse astrocytoma, DMLG: diffuse midline glioma, GBM: glioblastoma, KPS: Karnofsky performance status, O: oligodendroglioma, OS: overall survival, PA: pilocytic astrocytoma, WHO: World Health Organization.