Table 1.
Correlation Between Clinicopathological Features of ESCC Patients and the Expression Level of circ_0006168
| Characteristics | Number of Patients | circ_0006168 Expression | P value | |
|---|---|---|---|---|
| High | Low | |||
| Age (years) | 1.000 | |||
| ≥65 | 21 | 10 | 11 | |
| <65 | 9 | 5 | 4 | |
| Gender | 0.680 | |||
| Male | 22 | 12 | 10 | |
| Female | 8 | 3 | 5 | |
| Smoking | 0.456 | |||
| Smokers | 18 | 10 | 8 | |
| Never smokers | 12 | 5 | 7 | |
| Drinking history | 0.439 | |||
| Yes | 10 | 6 | 4 | |
| No | 20 | 9 | 11 | |
| Family history of ESCC | 1.000 | |||
| Yes | 5 | 3 | 2 | |
| None | 25 | 12 | 13 | |
| Cancer location | 0.904 | |||
| Upper | 6 | 3 | 3 | |
| Middle | 17 | 9 | 8 | |
| Lower | 7 | 3 | 4 | |
| Tumor size (cm) | 0.010* | |||
| ≥3(cm) | 17 | 12 | 5 | |
| <3(cm) | 13 | 3 | 10 | |
| Lymph node metastasis | 0.039* | |||
| Yes | 22 | 14 | 8 | |
| No | 8 | 1 | 7 | |
| TNM stage | 0.028* | |||
| IA-IIB | 14 | 4 | 10 | |
| IIIA-IV | 16 | 11 | 5 | |
Note: *P < 0.05, statistically significant.
Abbreviation: TNM, tumor node metastasis.