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. 2020 Jul 31;9(1):31–41. doi: 10.1016/j.prnil.2020.07.002

Fig. 3.

Fig. 3

hTERT-ADSC.sTRAIL line targets prostate cancer. (A), (B) The invasion study shows the migration of hTERT-ADSC or hTERT-ADSC.sTRAIL to prostate cancer. (C) Intracardiac delivery of hTERT-ADSC targeting prostate cancer. qPCR demonstrated GFP and human sTRAIL from experimentally induced prostate cancer tissues removed from the mice. (D) Expression of chemoattractant factors. The presence of the ligands, SCF, SDF-1, and VEGF in PC3 cells and their corresponding receptors c-kit, CXCR4, VEGFR1, VEGFR2, and VEGFR3 in hTERT-ADSC cells. ADCS = hTERT-ADSC, stem cell factor, SCF = stromal cell–derived factor, SDF = vascular endothelial growth factor, VEGF = vascular endothelial growth factor, VEGFR = vascular endothelial growth factor receptor, ADSC = hTERT immortalized human adipose stem cell line, ADSC.sTRAIL = sTRAIL-overexpressing ADSCs. ∗P < 0.05.